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Luna G3 vs. ResMed AirSense 11

Written by Jay Summer
UpdatedFebruary 02, 2026
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For many people, the next step after being diagnosed with sleep apnea is selecting a CPAP machine. The Luna G3 by React Health and the AirSense 11 by ResMed are two popular auto-CPAP options currently on the market. While both are designed to deliver effective therapy, they differ in areas like technology, design, and user experience that can influence day-to-day use.

Below, we compare the Luna G3 vs. ResMed AirSense 11, including which features they share in common, how they differ, and why you might prefer one over the other.

At a Glance

Luna G3 AirSense 11
Best For

CPAP users wanting a budget-friendly machine with high ratings and multiple comfort features

CPAP users wanting a popular, reputable brand, along with the latest tech in a companion app

Price

$849

$1,044

Available From

SleepDoctor.com

SleepDoctor.com

Why CPAP? And How to Choose One

By delivering air through a tube and mask, CPAP therapy helps keep your airway open during sleep, preventing lapses in breathing and snoring, as well as lowering the risk of chronic health conditions. Picking the right CPAP machine for you is a process that should involve input from your doctor or sleep specialist. They’ll take into account the severity of your sleep apnea, along with your personal preferences, budget, and comfort with tech features.

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Overview: Luna G3 vs. AirSense 11

The Luna G3 was released in 2021 and is manufactured by React Health, which was called 3B Medical at the time of the release. There are two CPAP models in the G3 line: the fixed-air CPAP model, called the LG3500, and the auto-CPAP machine, called the LG3600. 

React Health also has two bilevel PAP (BiPAP) devices under the Luna G3 line: the Bilevel 25A, called the LG3700, and the Bilevel ST 30Vt, called the LG3800. This comparison review focuses on the fixed and auto-CPAP Luna G3 units, not the BiPAP models. 

Both CPAP units come equipped with comfort features, like RESlex pressure relief, which lowers air pressure during exhalation. They also both have large screens and a physical dial to use for settings navigation. Heated humidification and heated tubing come standard on all Luna G3 models.

Like the Luna G3 models, the ResMed AirSense 11 was also released in 2021 and comes in both fixed-air and auto-CPAP versions.  ResMed also has a BiPAP machine as part of their 11 line, but they call it the AirCurve 11, rather than the AirSense. The fixed-air CPAP model is called the AirSense 11 Elite, while the auto-CPAP AirSense 11 is called the AutoSet. The AutoSet model comes with the option to use AutoSet for Her mode, which is a special algorithm tailored to treat sleep apnea in women.

The AirSense 11 has many comfort features, like the Luna G3. Because these machines share many similarities, it's helpful to look at their differences when trying to decide between them.

Product Specs

Luna G3 AirSense 11
Therapy Modes Options CPAP, APAP

Fixed, AutoSet, AutoSet for Her

Dimensions (HxWxD)

4.5" x 10.4" x 5.7"

3.72" x 10.21" x 5.45"

Weight

3.75 lbs.

2.5 lbs.

Sound Level

<28 dB

27 dBA

Pressure Range

4 to 20 cm H2O

4 to 20 cm H2O

User Controls Dial Touch Screen
Power Supply 65W 65W
Voltage Requirements 100V-240V AC, 24V DC 100-240V AC, 24V DC
Max Altitude 7,545 feet 9,870 feet
Connectivity Cellular

Bluetooth, Cellular

App Integration React Health PLUS myAir

Key Differences Between Luna G3 and AirSense 11

There are some key differences between the AirSense 11 and Luna G3. The AirSense 11 is a bit smaller and lighter, which may make it easier to travel with. While both models feature a screen that displays settings and data, the Luna G3 is controlled using a physical dial, while the AirSense 11 has a touch screen. The touch screen is a more advanced form of technology than the Luna G3's LCD screen, but some people prefer using a dial to navigate settings.

In terms of pressure and comfort features, these machines operate similarly. They both come in fixed-air models that release air at a steady rate of pressure, as well as auto-CPAP models that automatically adjust air pressure levels throughout the night based on need. Both have a ramp comfort feature, which allows pressure to gradually increase when the device is first turned on. Similarly, both have a pressure relief feature, which lowers air pressure at the beginning of each exhale. The noise level of each is nearly identical and are considered quiet CPAP machines.

Differences arise when you compare these devices in terms of connectivity. Both React Health and ResMed have companion apps that pair with the machines. The Luna G3 integrates with the React Health PLUS, and the AirSense 11 with myAir. But, the Luna G3 links to the app using a Cellular connection, while the AirSense 11 can use newer technology and update myAir via Bluetooth. Also, both apps display data about therapy usage, but myAir goes beyond that by providing assistance with set up, mask fit, troubleshooting, and more.

Features

Luna G3 AirSense 11
Humidifier

Built-in heated humidification

Built-in HumidAir

Ramp Feature

Time-based ramp up to 60 minutes

Time-based and AutoRamp options

Expiratory Pressure Relief

RESlex pressure relief option

EPR of 1, 2, or 3 cm H2O

Auto Start/Stop

Auto On and Auto Off options

SmartStart and SmartStop options

Therapy Data

Viewable in React Health PLUS, saved to SD card, and optional data transfer to care provider

Viewable in myAir, saved to SD card, and optional data transfer to care provider

Warranty

5 years

2 years

Full CPAP Comparison: Luna G3 vs. AirSense 11

Learn more about how the Luna G3 and AirSense 11 compare on specific features.

Design and Ease of Use

The Luna G3 and AirSense 11 have similar overall designs, but there are differences. Similarities include being operated by a power supply (rather than a battery), having a built-in water chamber that must be filled if heated humidification is used, and featuring a screen that displays settings and data.

Some design differences are apparent, however. The AirSense 11 is a bit smaller and lighter and features a more rounded, sleeker design. Aside from a large Start/Stop button on top, this model is primarily controlled via a touch screen. In contrast, the Luna G3 is controlled with a physical dial.

Therapy Modes and Pressure Features

These machines are nearly identical in terms of therapy modes and pressure features. Both come in fixed-pressure and auto-CPAP models. Both also come with ramp and pressure relief features that lower air pressure at key times to improve comfort.

The one major difference is that the AirSense 11 AutoSet, which is the auto-CPAP model, has AutoSet for Her, a proprietary algorithm developed to provide the best PAP therapy treatment for women, based on gender-specific breathing patterns.

Comfort and Noise

In addition to having air pressure-related comfort features, both of these machines also center sleepers' comfort through heated humidification, which can reduce dryness and discomfort. The Luna G3 always comes with heated tubing. Whether or not the AirSense 11 comes with heated tubing depends on where you purchase the machine from and can contribute to a higher price.

As far as noise goes, both of these devices are about as quiet as a whisper, but the AirSense 11 has been rated as 1 dB quieter than the Luna G3. Each machine also has an ambient light sensor and automatically adjusts the screen's brightness to match the light level in the room.

Smart Features and Data Tracking

Both the Luna G3 and the AirSense 11 have data tracking and share usage data on the machines' LCD screens, through companion apps, and to your healthcare provider, if desired. The AirSense 11 has the most up-to-date tech with its touch screen controls and Bluetooth connection options. The myAir app that connects with the AirSense 11 also offers a wider array of features beyond those offered by the React Health PLUS app.

Price and Insurance Considerations

The AirSense 11 tends to run roughly $150 more than the Luna G3 when it's sold with heated tubing. This price difference largely stems from the credibility of the ResMed name, as well as the advanced features offered through the myAir app.

If you plan on using insurance for your CPAP, talk to your insurance provider and doctor before placing an order for the device you prefer. They may need to give prior approval or have you place the order through a specific process in order to receive coverage.

Bottom Line: Which CPAP Machine Is Better for You?

Choose the Luna G3 if you:

  • Want comfort features like heated humidification, ramp, and pressure relief at a lower price point
  • Prefer using a physical dial to control settings instead of a touch screen
  • Don't need additional assistance with setup or troubleshooting through an app

Choose the AirSense 11 if you:

  • Prefer a slightly smaller, lighter, and sleeker CPAP model
  • Like having the latest technology, including a touch screen, Bluetooth, and advanced app features
  • Might want to access the proprietary AutoSet for Her algorithm, which is specially designed to treat sleep apnea in women

References

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